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Comparing nanoflow reversed-phase liquid chromatography-tandem mass spectrometry and capillary zone electrophoresis- tandem mass spectrometry for top-down proteomics
One of the major shortcomings in top-down proteomics is the lack of efficient separations for intact proteins that can be effectively coupled to mass spectrometry. Capillary zone electrophoresis (CZE) and nanoflow reversed-phase liquid chromatography (nanoRPLC) are two methods that can be coupled to...
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| Udgivet i: | Se Pu |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7545479/ https://ncbi.nlm.nih.gov/pubmed/31642259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3724/SP.J.1123.2019.05001 |
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