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Spatial learning and long‐term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice

BACKGROUND: RasGrf1 is a guanine‐nucleotide releasing factor that enhances Ras activity. Human PTTG1 is an oncoprotein found in pituitary tumors and later identified as securin, a protein isolated from yeast with a reported role in chromosome separation. It has been suggested that RasGrf1 is an impo...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Manyes, Lara, Holst, Sarah, Lozano, Manuel, Santos, Eugenio, Fernandez‐Medarde, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236249/
https://ncbi.nlm.nih.gov/pubmed/30259712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1089
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