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Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

BACKGROUND: Our prior characterization of RasGrf1 deficient mice uncovered significant defects in pancreatic islet count and size as well as beta cell development and signaling function, raising question about the mechanisms linking RasGrf1 to the generation of those “pancreatic” phenotypes. RESULTS...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Manyes, Lara, Arribas, Monica, Gomez, Carmela, Calzada, Nuria, Fernandez-Medarde, Alberto, Santos, Eugenio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301450/
https://ncbi.nlm.nih.gov/pubmed/25421944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1019
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