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Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells

BACKGROUND: Our prior characterization of RasGrf1 deficient mice uncovered significant defects in pancreatic islet count and size as well as beta cell development and signaling function, raising question about the mechanisms linking RasGrf1 to the generation of those “pancreatic” phenotypes. RESULTS...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Genomics
Hauptverfasser: Manyes, Lara, Arribas, Monica, Gomez, Carmela, Calzada, Nuria, Fernandez-Medarde, Alberto, Santos, Eugenio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301450/
https://ncbi.nlm.nih.gov/pubmed/25421944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1019
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