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Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival
The nuclear translocation of endogenous heat shock cognate protein HSPA8 is a requisite for cell survival during oxidative and heat shock stress. Upon these events, cytoplasmic HSPA8 is thought to concentrate within the nucleus and nucleolus. When the situation returns to normal, HSPA8 is released f...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6235846/ https://ncbi.nlm.nih.gov/pubmed/30429537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34887-6 |
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