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Lysosomes as a therapeutic target
Lysosomes are membrane-bound organelles with roles in processes involved in degrading and recycling cellular waste, cellular signalling and energy metabolism. Defects in genes encoding lysosomal proteins cause lysosomal storage disorders, in which enzyme replacement therapy has proved successful. Gr...
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| Publicado no: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7097195/ https://ncbi.nlm.nih.gov/pubmed/31477883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0036-1 |
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