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Lysosomes as a therapeutic target
Lysosomes are membrane-bound organelles with roles in processes involved in degrading and recycling cellular waste, cellular signalling and energy metabolism. Defects in genes encoding lysosomal proteins cause lysosomal storage disorders, in which enzyme replacement therapy has proved successful. Gr...
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| Pubblicato in: | Nat Rev Drug Discov |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7097195/ https://ncbi.nlm.nih.gov/pubmed/31477883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-019-0036-1 |
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