Targeting cIAPs, a New Option for Functional Cure of Chronic Hepatitis B Infection?

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• Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2
  per: Darding, M, et al.
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• LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC
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• Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2
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