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MECHANISM OF CYTOKINESIS FAILURE IN OVARIAN CYSTADENOMAS WITH DEFECTIVE BRCA1 AND P53 PATHWAYS

We previously described an in vitro model in which serous ovarian cystadenomas were transfected with SV40 large T antigen, resulting in loss of RB and P53 functions and thus mimicking genetic defects present in early high-grade serous extra-uterine Müllerian (traditionally called high-grade serous o...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Austria, Theresa, Marion, Christine, Yu, Vanessa, Widschwendter, Martin, Hinton, David R., Dubeau, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235723/
https://ncbi.nlm.nih.gov/pubmed/29978915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31659
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