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Lentiviral Mediated Production of Transgenic Mice: A Simple and Highly Efficient Method for Direct Study of Founders

For almost 40 years, pronuclear DNA injection represents the standard method to generate transgenic mice with random integration of transgenes. Such a routine procedure is widely utilized throughout the world and its main limitation resides in the poor efficacy of transgene integration, resulting in...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Dussaud, Sébastien, Pardanaud-Glavieux, Corinne, Sauty-Colace, Claire, Ravassard, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235436/
https://ncbi.nlm.nih.gov/pubmed/30346378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57609
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