Regulation of RIP3 protein stability by PELI1-mediated proteasome-dependent degradation

Receptor-interacting protein kinase-3 (RIP3 or RIPK3) is a serine-threonine kinase largely essential for necroptotic cell death; it also plays a role in some inflammatory diseases. High levels of RIP3 are likely sufficient to activate necroptotic and inflammatory pathways downstream of RIP3 in the a...

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Publicat a:BMB Rep
Autors principals: Park, Han-Hee, Morgan, Michael J., Kang, Ho Chul, Kim, You-Sun
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Biochemistry and Molecular Biology 2018
Matèries:
Perspective
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235095/
https://ncbi.nlm.nih.gov/pubmed/30269743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2018.51.10.217
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