HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis

Necroptosis is a type of programmed cell death that usually occurs under apoptosis-deficient conditions. Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is a central player in necroptosis, and its kinase activity is essential for downstream necroptotic signaling events. Since RIP3 kinase acti...

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Vydáno v:Exp Mol Med
Hlavní autoři: Park, Han-Hee, Park, Se-Yeon, Mah, Shinmee, Park, Jung-Hee, Hong, Soon-Sun, Hong, Sungwoo, Kim, You-Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148246/
https://ncbi.nlm.nih.gov/pubmed/30237400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0152-8
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