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HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis
Necroptosis is a type of programmed cell death that usually occurs under apoptosis-deficient conditions. Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is a central player in necroptosis, and its kinase activity is essential for downstream necroptotic signaling events. Since RIP3 kinase acti...
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| Publicado no: | Exp Mol Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6148246/ https://ncbi.nlm.nih.gov/pubmed/30237400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0152-8 |
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