Mealtime dosing of a rapid-acting insulin analog reduces glucose variability and suppresses daytime cardiac sympathetic activity: a randomized controlled study in hospitalized patients with type 2 diabetes

OBJECTIVE: Glucose variability induces endothelial dysfunction and cardiac autonomic nerve abnormality. Here we compared the effects of mealtime insulin aspart and bedtime insulin detemir on glucose variability, endothelial function, and cardiac autonomic nerve activity among Japanese patients with...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMJ Open Diabetes Res Care
Prif Awduron: Kanamori, Takehiro, Takeshita, Yumie, Isobe, Yuki, Kato, Ken-ichiro, Misu, Hirofumi, Kaneko, Shuichi, Takamura, Toshinari
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2018
Pynciau:
Cardiovascular and Metabolic Risk
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235056/
https://ncbi.nlm.nih.gov/pubmed/30487974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2018-000588
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