Mealtime dosing of a rapid-acting insulin analog reduces glucose variability and suppresses daytime cardiac sympathetic activity: a randomized controlled study in hospitalized patients with type 2 diabetes

OBJECTIVE: Glucose variability induces endothelial dysfunction and cardiac autonomic nerve abnormality. Here we compared the effects of mealtime insulin aspart and bedtime insulin detemir on glucose variability, endothelial function, and cardiac autonomic nerve activity among Japanese patients with...

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Bibliographic Details
Published in:BMJ Open Diabetes Res Care
Main Authors: Kanamori, Takehiro, Takeshita, Yumie, Isobe, Yuki, Kato, Ken-ichiro, Misu, Hirofumi, Kaneko, Shuichi, Takamura, Toshinari
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2018
Subjects:
Cardiovascular and Metabolic Risk
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235056/
https://ncbi.nlm.nih.gov/pubmed/30487974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2018-000588
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