Mealtime dosing of a rapid-acting insulin analog reduces glucose variability and suppresses daytime cardiac sympathetic activity: a randomized controlled study in hospitalized patients with type 2 diabetes

OBJECTIVE: Glucose variability induces endothelial dysfunction and cardiac autonomic nerve abnormality. Here we compared the effects of mealtime insulin aspart and bedtime insulin detemir on glucose variability, endothelial function, and cardiac autonomic nerve activity among Japanese patients with...

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Pubblicato in:BMJ Open Diabetes Res Care
Autori principali: Kanamori, Takehiro, Takeshita, Yumie, Isobe, Yuki, Kato, Ken-ichiro, Misu, Hirofumi, Kaneko, Shuichi, Takamura, Toshinari
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2018
Soggetti:
Cardiovascular and Metabolic Risk
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235056/
https://ncbi.nlm.nih.gov/pubmed/30487974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2018-000588
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