Mealtime dosing of a rapid-acting insulin analog reduces glucose variability and suppresses daytime cardiac sympathetic activity: a randomized controlled study in hospitalized patients with type 2 diabetes

OBJECTIVE: Glucose variability induces endothelial dysfunction and cardiac autonomic nerve abnormality. Here we compared the effects of mealtime insulin aspart and bedtime insulin detemir on glucose variability, endothelial function, and cardiac autonomic nerve activity among Japanese patients with...

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Publicado en:BMJ Open Diabetes Res Care
Main Authors: Kanamori, Takehiro, Takeshita, Yumie, Isobe, Yuki, Kato, Ken-ichiro, Misu, Hirofumi, Kaneko, Shuichi, Takamura, Toshinari
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2018
Assuntos:
Cardiovascular and Metabolic Risk
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235056/
https://ncbi.nlm.nih.gov/pubmed/30487974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2018-000588
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