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Genetic interactions between the Aurora kinases reveal new requirements for AURKB and AURKC during oocyte meiosis
SUMMARY: Errors in chromosome segregation during female meiosis I occur frequently, and aneuploid embryos account for 1/3 of all miscarriages in humans [1]. Unlike mitotic cells that require two Aurora kinase (AURK) homologs to help prevent aneuploidy (AURKA, AURKB), mammalian germ cells also requir...
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| Pubblicato in: | Curr Biol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6234855/ https://ncbi.nlm.nih.gov/pubmed/30415701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.08.052 |
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