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Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes

Meiosis I (MI), the division that generates haploids, is prone to errors that lead to aneuploidy in females. Haspin is a kinase that phosphorylates histone H3 on threonine 3, thereby recruiting Aurora kinase B (AURKB) and the chromosomal passenger complex (CPC) to kinetochores to regulate mitosis. H...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Nguyen, Alexandra L., Gentilello, Amanda S., Balboula, Ahmed Z., Shrivastava, Vibha, Ohring, Jacob, Schindler, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248095/
https://ncbi.nlm.nih.gov/pubmed/25315835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.158840
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