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Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes
Meiosis I (MI), the division that generates haploids, is prone to errors that lead to aneuploidy in females. Haspin is a kinase that phosphorylates histone H3 on threonine 3, thereby recruiting Aurora kinase B (AURKB) and the chromosomal passenger complex (CPC) to kinetochores to regulate mitosis. H...
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| Publié dans: | J Cell Sci |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248095/ https://ncbi.nlm.nih.gov/pubmed/25315835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.158840 |
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