Utility of Glycosylated TIMP3 molecules: Inhibition of MMPs and TACE to improve cardiac function in rat myocardial infarct model

Tissue Inhibitor of Metalloproteinase 3 (TIMP3) is a secreted protein that has a great utility to inhibit elevated metalloproteinase (MMP) activity in injured tissues including infarcted cardiac tissue, inflamed vessels, and joint cartilages. An imbalance between TIMP3 and active MMP levels in the l...

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Bibliografske podrobnosti
izdano v:Pharmacol Res Perspect
Main Authors: Chintalgattu, Vishnu, Greenberg, Joanne, Singh, Shivani, Chiueh, Venice, Gilbert, Amy, O'Neill, Jason W., Smith, Stephen, Jackson, Simon, Khakoo, Aarif Y., Lee, TaeWeon
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234480/
https://ncbi.nlm.nih.gov/pubmed/30459952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.442
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