Native and Polyubiquitinated Forms of Dihydroceramide Desaturase Are Differentially Linked to Human Embryonic Kidney Cell Survival

There is controversy concerning the role of dihydroceramide desaturase (Degs1) in regulating cell survival, with studies showing that it can both promote and protect against apoptosis. We have therefore investigated the molecular basis for these opposing roles of Degs1. Treatment of HEK293T cells wi...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Alsanafi, Mariam, Kelly, Samuel L., Jubair, Karawan, McNaughton, Melissa, Tate, Rothwelle J., Merrill, Alfred H., Pyne, Susan, Pyne, Nigel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234290/
https://ncbi.nlm.nih.gov/pubmed/30224516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00222-18
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