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Differentiating between testicular toxicity and sexual immaturity in ortho-phthalaldehyde inhalation toxicity studies in rats and mice

Early deaths of young or juvenile animals (before sexual maturation is achieved) in routine regulatory safety studies present pathologists and toxicologists with the challenge of interpreting findings in the male reproductive tract. Additionally, the advent of toxicity testing regulations have resul...

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Detalhes bibliográficos
Publicado no:Toxicol Pathol
Main Authors: Catlin, Natasha R., Willson, Cynthia J., Creasy, Dianne M., Rao, Deepa B., Kissling, Grace E., McIntyre, Barry S., Wyde, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234048/
https://ncbi.nlm.nih.gov/pubmed/30259793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623318801790
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