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Differentiating between testicular toxicity and sexual immaturity in ortho-phthalaldehyde inhalation toxicity studies in rats and mice

Early deaths of young or juvenile animals (before sexual maturation is achieved) in routine regulatory safety studies present pathologists and toxicologists with the challenge of interpreting findings in the male reproductive tract. Additionally, the advent of toxicity testing regulations have resul...

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Библиографические подробности
Опубликовано в: :Toxicol Pathol
Главные авторы: Catlin, Natasha R., Willson, Cynthia J., Creasy, Dianne M., Rao, Deepa B., Kissling, Grace E., McIntyre, Barry S., Wyde, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234048/
https://ncbi.nlm.nih.gov/pubmed/30259793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623318801790
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