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Dynamic neuromuscular remodeling precedes motor-unit loss in a mouse model of ALS
Despite being an early event in ALS, it remains unclear whether the denervation of neuromuscular junctions (NMJ) is simply the first manifestation of a globally degenerating motor neuron. Using in vivo imaging of single axons and their NMJs over a three-month period, we identify that single motor-un...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6234026/ https://ncbi.nlm.nih.gov/pubmed/30320556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41973 |
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