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Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS

Hyperexcitability has been suggested to contribute to motoneuron degeneration in amyotrophic lateral sclerosis (ALS). If this is so, and given that the physiological type of a motor unit determines the relative susceptibility of its motoneuron in ALS, then one would expect the most vulnerable motone...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Martínez-Silva, María de Lourdes, Imhoff-Manuel, Rebecca D, Sharma, Aarti, Heckman, CJ, Shneider, Neil A, Roselli, Francesco, Zytnicki, Daniel, Manuel, Marin
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922970/
https://ncbi.nlm.nih.gov/pubmed/29580378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30955
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