Dietary restriction improves intestinal cellular fitness to enhance gut barrier function and lifespan in D. melanogaster

Loss of gut integrity is linked to various human diseases including inflammatory bowel disease. However, the mechanisms that lead to loss of barrier function remain poorly understood. Using D. melanogaster, we demonstrate that dietary restriction (DR) slows the age-related decline in intestinal inte...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Akagi, Kazutaka, Wilson, Kenneth A., Katewa, Subhash D., Ortega, Mauricio, Simons, Jesse, Hilsabeck, Tyler A., Kapuria, Subir, Sharma, Amit, Jasper, Heinrich, Kapahi, Pankaj
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233930/
https://ncbi.nlm.nih.gov/pubmed/30383748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007777
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