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Intestinal IRE1 is required for increased triglyceride metabolism and longer lifespan under Dietary Restriction
Dietary restriction (DR) is one of the most robust lifespan-extending interventions in animals. The beneficial effects of DR involve a metabolic adaptation towards increased triglyceride usage. The regulatory mechanism and the tissue specificity of this metabolic switch remain unclear. Here we show...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089850/ https://ncbi.nlm.nih.gov/pubmed/27783936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.003 |
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