Peripheral circadian clocks mediate dietary restriction dependent changes in lifespan and fat metabolism in Drosophila

Endogenous circadian clocks orchestrate several metabolic and signaling pathways that are known to modulate lifespan, suggesting clocks as potential targets for manipulation of metabolism and lifespan. We report here that the core circadian clock genes, timeless (tim) and period (per), are required...

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Pubblicato in:Cell Metab
Autori principali: Katewa, Subhash D., Akagi, Kazutaka, Bose, Neelanjan, Rakshit, Kuntol, Camarella, Timothy, Zheng, Xiangzhong, Hall, David, Davis, Sonnet, Nelson, Christopher S., Brem, Rachel B., Ramanathan, Arvind, Sehgal, Amita, Giebultowicz, Jadwiga M., Kapahi, Pankaj
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715572/
https://ncbi.nlm.nih.gov/pubmed/26626459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.10.014
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