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(Radio)Fluoro-Click Reaction Enabled by a Hydrogen Bonding Cluster

We have developed a widely applicable nucleophilic (radio)fluoro-click reaction of ynamides with readily available and easy handling KF((18)F). The reactions exhibited high functional group tolerance and needed only ambient atmosphere. Most importantly, this is the first (18)F addition protocol to C...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zeng, Xiaojun, Li, Junling, Ng, Chin K., Hammond, Gerald B., Xu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233894/
https://ncbi.nlm.nih.gov/pubmed/29276938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201711341
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