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(Radio)Fluoro-Click Reaction Enabled by a Hydrogen Bonding Cluster

We have developed a widely applicable nucleophilic (radio)fluoro-click reaction of ynamides with readily available and easy handling KF((18)F). The reactions exhibited high functional group tolerance and needed only ambient atmosphere. Most importantly, this is the first (18)F addition protocol to C...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Zeng, Xiaojun, Li, Junling, Ng, Chin K., Hammond, Gerald B., Xu, Bo
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233894/
https://ncbi.nlm.nih.gov/pubmed/29276938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201711341
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