Integrating Drug’s Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is complex in mechanism. Different drugs could undergo different mechanisms but result in the same DILI type while the same drug could lead to different DILI types via different mechanisms. Therefore, predicting a drug’s potential for DILI should take its underlying...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Wu, Leihong, Liu, Zhichao, Auerbach, Scott, Huang, Ruili, Chen, Minjun, McEuen, Kristin, Xu, Joshua, Fang, Hong, Tong, Weida
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233892/
https://ncbi.nlm.nih.gov/pubmed/28350954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.6b00719
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados