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Integrating Drug’s Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is complex in mechanism. Different drugs could undergo different mechanisms but result in the same DILI type while the same drug could lead to different DILI types via different mechanisms. Therefore, predicting a drug’s potential for DILI should take its underlying...

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Bibliografische gegevens
Gepubliceerd in:J Chem Inf Model
Hoofdauteurs: Wu, Leihong, Liu, Zhichao, Auerbach, Scott, Huang, Ruili, Chen, Minjun, McEuen, Kristin, Xu, Joshua, Fang, Hong, Tong, Weida
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233892/
https://ncbi.nlm.nih.gov/pubmed/28350954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.6b00719
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