LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer

BACKGROUND: Reprogrammed energy metabolism has become an emerging hallmark of cancer in recent years. Transporters have been reported to be amino acid sensors involved in controlling mTOR recruitment and activation, which is crucial for the growth of both normal and tumor cells. L-type amino acid tr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Feng, Mengyu, Xiong, Guangbing, Cao, Zhe, Yang, Gang, Zheng, Suli, Qiu, Jiangdong, You, Lei, Zheng, Lianfang, Zhang, Taiping, Zhao, Yupei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233565/
https://ncbi.nlm.nih.gov/pubmed/30419950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0947-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados