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Endocytosis and Intracellular Trafficking of Notch and its ligands

Notch signaling occurs through direct interaction between Notch, the receptor, and its ligands, presented on the surface of neighboring cells. Endocytosis has been shown to be essential for Notch signal activation in both signal-sending and signal-receiving cells and numerous genes involved in vesic...

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Bibliographic Details
Published in:Curr Top Dev Biol
Main Authors: Yamamoto, Shinya, Charng, Wu-Lin, Bellen, Hugo J
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233319/
https://ncbi.nlm.nih.gov/pubmed/20816395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0070-2153(10)92005-X
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