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Critical computational analysis illuminates the reductive-elimination mechanism that activates nitrogenase for N(2) reduction

Recent spectroscopic, kinetic, photophysical, and thermodynamic measurements show activation of nitrogenase for N(2) → 2NH(3) reduction involves the reductive elimination (re) of H(2) from two [Fe–H–Fe] bridging hydrides bound to the catalytic [7Fe–9S–Mo–C–homocitrate] FeMo-cofactor (FeMo-co). These...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Raugei, Simone, Seefeldt, Lance C., Hoffman, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233137/
https://ncbi.nlm.nih.gov/pubmed/30355772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810211115
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