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Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Receptor-type protein tyrosine phosphatase D (PTPRD) is a neuronal cell-adhesion molecule/synaptic specifier that has been implicated in addiction vulnerability and stimulant reward by human genomewide association and mouse cocaine-conditioned place-preference data. However, there have been no repor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Uhl, George R., Martinez, Maria J., Paik, Paul, Sulima, Agnieszka, Bi, Guo-Hua, Iyer, Malliga R., Gardner, Eliot, Rice, Kenner C., Xi, Zheng-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233130/
https://ncbi.nlm.nih.gov/pubmed/30348770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720446115
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