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Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development

Codevelopment of the lungs and heart underlies key evolutionary innovations in the transition to terrestrial life. Cardiac specializations that support pulmonary circulation, including the atrial septum, are generated by second heart field (SHF) cardiopulmonary progenitors (CPPs). It has been presum...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Steimle, Jeffrey D., Rankin, Scott A., Slagle, Christopher E., Bekeny, Jenna, Rydeen, Ariel B., Chan, Sunny Sun-Kin, Kweon, Junghun, Yang, Xinan H., Ikegami, Kohta, Nadadur, Rangarajan D., Rowton, Megan, Hoffmann, Andrew D., Lazarevic, Sonja, Thomas, William, Boyle Anderson, Erin A. T., Horb, Marko E., Luna-Zurita, Luis, Ho, Robert K., Kyba, Michael, Jensen, Bjarke, Zorn, Aaron M., Conlon, Frank L., Moskowitz, Ivan P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233116/
https://ncbi.nlm.nih.gov/pubmed/30352852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811624115
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