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TBX5: A Key Regulator of Heart Development

TBX5 is a member of the T-box transcription factor family and is primarily known for its role in cardiac and forelimb development. Human patients with dominant mutations in TBX5 are characterized by Holt–Oram syndrome, and show defects of the cardiac septa, cardiac conduction system, and the anterio...

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Detalhes bibliográficos
Publicado no:Curr Top Dev Biol
Main Authors: Steimle, J.D., Moskowitz, I.P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371404/
https://ncbi.nlm.nih.gov/pubmed/28057264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ctdb.2016.08.008
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