Small-molecule Ca(V)α(1)⋅Ca(V)β antagonist suppresses neuronal voltage-gated calcium-channel trafficking

Extracellular calcium flow through neuronal voltage-gated Ca(V)2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the postsynaptic central nociceptive neurons. The C...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Chen, Xingjuan, Liu, Degang, Zhou, Donghui, Si, Yubing, Xu, David, Stamatkin, Christopher W., Ghozayel, Mona K., Ripsch, Matthew S., Obukhov, Alexander G., White, Fletcher A., Meroueh, Samy O.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233087/
https://ncbi.nlm.nih.gov/pubmed/30355767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813157115
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