Asynchronous Ca(2)(+) current conducted by voltage-gated Ca(2+) (Ca(V))-2.1 and Ca(V)2.2 channels and its implications for asynchronous neurotransmitter release

We have identified an asynchronously activated Ca(2+) current through voltage-gated Ca(2+) (Ca(V))-2.1 and Ca(V)2.2 channels, which conduct P/Q- and N-type Ca(2+) currents that initiate neurotransmitter release. In nonneuronal cells expressing Ca(V)2.1 or Ca(V)2.2 channels and in hippocampal neurons...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Few, Alexandra P., Nanou, Evanthia, Watari, Hirofumi, Sullivan, Jane M., Scheuer, Todd, Catterall, William A.
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2012
الموضوعات:
PNAS Plus
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289374/
https://ncbi.nlm.nih.gov/pubmed/22308469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121103109
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