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Calcium sensor regulation of the Ca(V)2.1 Ca(2+) channel contributes to short-term synaptic plasticity in hippocampal neurons

Short-term synaptic plasticity is induced by calcium (Ca(2+)) accumulating in presynaptic nerve terminals during repetitive action potentials. Regulation of voltage-gated Ca(V)2.1 Ca(2+) channels by Ca(2+) sensor proteins induces facilitation of Ca(2+) currents and synaptic facilitation in cultured...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nanou, Evanthia, Sullivan, Jane M., Scheuer, Todd, Catterall, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743814/
https://ncbi.nlm.nih.gov/pubmed/26755594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524636113
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