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Interstitial flow promotes macrophage polarization toward an M2 phenotype

Tumor tissues are characterized by an elevated interstitial fluid flow from the tumor to the surrounding stroma. Macrophages in the tumor microenvironment are key contributors to tumor progression. While it is well established that chemical stimuli within the tumor tissues can alter macrophage behav...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Li, Ran, Serrano, Jean Carlos, Xing, Hao, Lee, Tara A., Azizgolshani, Hesham, Zaman, Muhammad, Kamm, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232969/
https://ncbi.nlm.nih.gov/pubmed/29995595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-03-0164
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