Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype

It is established that the adipocyte-derived cytokine adiponectin protects against cardiovascular and metabolic diseases, but the effect of this adipokine on macrophage polarization, an important mediator of disease progression, has never been assessed. We hypothesized that adiponectin modulates mac...

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Detalhes bibliográficos
Main Authors: Ohashi, Koji, Parker, Jennifer L., Ouchi, Noriyuki, Higuchi, Akiko, Vita, Joseph A., Gokce, Noyan, Pedersen, Anette Amstrup, Kalthoff, Christoph, Tullin, Søren, Sams, Anette, Summer, Ross, Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825410/
https://ncbi.nlm.nih.gov/pubmed/20028977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088708
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