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Interstitial flow promotes macrophage polarization toward an M2 phenotype

Tumor tissues are characterized by an elevated interstitial fluid flow from the tumor to the surrounding stroma. Macrophages in the tumor microenvironment are key contributors to tumor progression. While it is well established that chemical stimuli within the tumor tissues can alter macrophage behav...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Li, Ran, Serrano, Jean Carlos, Xing, Hao, Lee, Tara A., Azizgolshani, Hesham, Zaman, Muhammad, Kamm, Roger D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232969/
https://ncbi.nlm.nih.gov/pubmed/29995595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-03-0164
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