Similar Gastro-Intestinal Exposure to Florfenicol After Oral or Intramuscular Administration in Pigs, Leading to Resistance Selection in Commensal Escherichia coli

Florfenicol, which is licensed for veterinary use only, proves to be a potent antimicrobial for treatment of respiratory disease. However, the subsequent exposure of the gut microbiota to florfenicol is not well described. Hence, the effect of various administration protocols on both plasma and gast...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: De Smet, Joren, Boyen, Filip, Croubels, Siska, Rasschaert, Geertrui, Haesebrouck, Freddy, De Backer, Patrick, Devreese, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232271/
https://ncbi.nlm.nih.gov/pubmed/30459619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01265
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