Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation

Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector protein via the cag-Type IV Secretion System (cag-T4SS) into host cells is a hallmark of infection with Hp and a major risk factor for severe gastric diseases, including gastric cancer. To mediate the injection...

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Udgivet i:PLoS Pathog
Main Authors: Zhao, Qing, Busch, Benjamin, Jiménez-Soto, Luisa Fernanda, Ishikawa-Ankerhold, Hellen, Massberg, Steffen, Terradot, Laurent, Fischer, Wolfgang, Haas, Rainer
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231679/
https://ncbi.nlm.nih.gov/pubmed/30365569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007359
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