The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA

Helicobacter pylori infects half of the world's population, and strains that encode the cag type IV secretion system for injection of the oncoprotein CagA into host gastric epithelial cells are associated with elevated levels of cancer. CagA translocation into host cells is dependent on interac...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Bonsor, Daniel A, Zhao, Qing, Schmidinger, Barbara, Weiss, Evelyn, Wang, Jingheng, Deredge, Daniel, Beadenkopf, Robert, Dow, Blaine, Fischer, Wolfgang, Beckett, Dorothy, Wintrode, Patrick L, Haas, Rainer, Sundberg, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028028/
https://ncbi.nlm.nih.gov/pubmed/29724755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798664
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