The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA

Helicobacter pylori infects half of the world's population, and strains that encode the cag type IV secretion system for injection of the oncoprotein CagA into host gastric epithelial cells are associated with elevated levels of cancer. CagA translocation into host cells is dependent on interac...

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Veröffentlicht in:EMBO J
Hauptverfasser: Bonsor, Daniel A, Zhao, Qing, Schmidinger, Barbara, Weiss, Evelyn, Wang, Jingheng, Deredge, Daniel, Beadenkopf, Robert, Dow, Blaine, Fischer, Wolfgang, Beckett, Dorothy, Wintrode, Patrick L, Haas, Rainer, Sundberg, Eric J
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028028/
https://ncbi.nlm.nih.gov/pubmed/29724755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798664
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