Cysteine Residues in Helicobacter pylori Adhesin HopQ Are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation

Attachment to the host gastric mucosa is a key step in Helicobacter pylori infection. Recently, a novel adhesin, HopQ, was shown to bind distinct host CEACAM proteins—an interaction that was found to be essential for the translocation of CagA, a key virulence factor of H. pylori. The HopQ–CEACAM1 co...

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Bibliographic Details
Published in:Microorganisms
Main Authors: Hamway, Youssef, Taxauer, Karin, Moonens, Kristof, Neumeyer, Victoria, Fischer, Wolfgang, Schmitt, Verena, Singer, Bernhard B., Remaut, Han, Gerhard, Markus, Mejías-Luque, Raquel
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232459/
https://ncbi.nlm.nih.gov/pubmed/32218315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8040465
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