Elucidating the molecular pathogenesis of glioma: integrated germline and somatic profiling of a familial glioma case series

BACKGROUND: The genomic characterization of sporadically arising gliomas has delineated molecularly and clinically distinct subclasses of disease. However, less is known about the molecular nature of gliomas that are familial in origin. We performed molecular subtyping of 163 tumor specimens from in...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Jacobs, Daniel I, Fukumura, Kazutaka, Bainbridge, Matthew N, Armstrong, Georgina N, Tsavachidis, Spiridon, Gu, Xiangjun, Doddapaneni, Harsha V, Hu, Jianhong, Jayaseelan, Joy C, Muzny, Donna M, Huse, Jason T, Bondy, Melissa L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231201/
https://ncbi.nlm.nih.gov/pubmed/30165405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy119
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