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Tumor somatic mutations also existing as germline polymorphisms may help to identify functional SNPs from genome-wide association studies
We hypothesized that a joint analysis of cancer risk-associated single-nucleotide polymorphism (SNP) and somatic mutations in tumor samples can predict functional and potentially causal SNPs from GWASs. We used mutations reported in the Catalog of Somatic Mutations in Cancer (COSMIC). Confirmed soma...
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| Publicado no: | Carcinogenesis |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566444/ https://ncbi.nlm.nih.gov/pubmed/32681635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgaa077 |
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