CARM1-mediated methylation of protein arginine methyltransferase 5 represses human γ-globin gene expression in erythroleukemia cells

Protein arginine methyltransferase 5 (PRMT5) is a member of the arginine methyltransferase protein family that critically mediates the symmetric dimethylation of Arg-3 at histone H4 (H4R3me2s) and is involved in many key cellular processes, including hematopoiesis. However, the post-translational mo...

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Vydáno v:J Biol Chem
Hlavní autoři: Nie, Min, Wang, Yadong, Guo, Chan, Li, Xinyu, Wang, Ying, Deng, Yexuan, Yao, Bing, Gui, Tao, Ma, Chi, Liu, Ming, Wang, Panxue, Wang, Ruoyun, Tan, Renxiang, Fang, Ming, Chen, Bing, He, Yinghong, Huang, David C. S., Ju, Junyi, Zhao, Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231142/
https://ncbi.nlm.nih.gov/pubmed/30257864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004028
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