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The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium

RAB28, a member of the RAS oncogene family, is a ubiquitous, farnesylated, small GTPase of unknown function present in photoreceptors and the retinal pigmented epithelium (RPE). Nonsense mutations of the human RAB28 gene cause recessive cone-rod dystrophy 18 (CRD18), characterized by macular hyperpi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ying, Guoxin, Boldt, Karsten, Ueffing, Marius, Gerstner, Cecilia D., Frederick, Jeanne M., Baehr, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231133/
https://ncbi.nlm.nih.gov/pubmed/30228185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005484
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